Antibody prevalence to the 2009 pandemic influenza A (H1N1) virus in Germany: geographically variable immunity in winter 2010/2011
Identifieur interne : 000B35 ( Main/Exploration ); précédent : 000B34; suivant : 000B36Antibody prevalence to the 2009 pandemic influenza A (H1N1) virus in Germany: geographically variable immunity in winter 2010/2011
Auteurs : Anne Hackenberg [Allemagne] ; Gökhan Arman-Kalcek [Allemagne] ; Jens Hiller [Allemagne] ; Gülsah Gabriel [Allemagne]Source :
- Medical Microbiology and Immunology [ 0300-8584 ] ; 2013-02-01.
Descripteurs français
- Wicri :
- geographic : Allemagne.
English descriptors
Abstract
Abstract: Location- and age-specific prevalence of antibodies against 2009 pandemic influenza A (H1N1) virus were determined in sera of blood donors collected during winter 2010/2011 in Germany. Prevalence of antibodies at protective titres (HI ≥1:40) varied significantly between cities (24.13–83.67 %) throughout all age groups. However, high level antibodies (HI >1:80) were most prevalent among young individuals (18–29 and 30–39 years). Overall, this study demonstrates that older people (50–59 and 60–70 years) are no longer more likely to present protective antibody titres against 2009 pandemic influenza A (H1N1) virus than younger individuals. Furthermore, our data show a highly variable immunity among the German population in different major cities almost 2 years after the detection of first cases in Germany.
Url:
DOI: 10.1007/s00430-012-0251-4
Affiliations:
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type="abstract" xml:lang="en">Abstract: Location- and age-specific prevalence of antibodies against 2009 pandemic influenza A (H1N1) virus were determined in sera of blood donors collected during winter 2010/2011 in Germany. Prevalence of antibodies at protective titres (HI ≥1:40) varied significantly between cities (24.13–83.67 %) throughout all age groups. However, high level antibodies (HI >1:80) were most prevalent among young individuals (18–29 and 30–39 years). Overall, this study demonstrates that older people (50–59 and 60–70 years) are no longer more likely to present protective antibody titres against 2009 pandemic influenza A (H1N1) virus than younger individuals. Furthermore, our data show a highly variable immunity among the German population in different major cities almost 2 years after the detection of first cases in Germany.</div></front></TEI><affiliations><list><country><li>Allemagne</li></country><region><li>Hambourg</li></region><settlement><li>Hambourg</li></settlement></list><tree><country name="Allemagne"><region name="Hambourg"><name sortKey="Hackenberg, Anne" sort="Hackenberg, Anne" uniqKey="Hackenberg A" first="Anne" last="Hackenberg">Anne Hackenberg</name></region><name sortKey="Arman Kalcek, Gokhan" sort="Arman Kalcek, Gokhan" uniqKey="Arman Kalcek G" first="Gökhan" last="Arman-Kalcek">Gökhan Arman-Kalcek</name><name sortKey="Gabriel, Gulsah" sort="Gabriel, Gulsah" uniqKey="Gabriel G" first="Gülsah" last="Gabriel">Gülsah Gabriel</name><name sortKey="Gabriel, Gulsah" sort="Gabriel, Gulsah" uniqKey="Gabriel G" first="Gülsah" last="Gabriel">Gülsah Gabriel</name><name sortKey="Hiller, Jens" sort="Hiller, Jens" uniqKey="Hiller J" first="Jens" last="Hiller">Jens Hiller</name></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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